Our research resulted in over 100 articles published in international, peer reviewed journals, spanning the fields of biochemistry, medicinal chemistry, and computational chemistry. A selection of papers representative of our current research interests is presented below.

For a complete list of Dr. Costanzi’s papers see: https://scholar.google.com/citations?user=nLhaKzoAAAAJ

Influence of the Structural Accuracy of Homology Models on Their Applicability to Docking-Based Virtual Screening: The β2 Adrenergic Receptor as a Case Study.

Costanzi S, Cohen A, Danfora A, Dolatmoradi M

Journal of Chemical Information and Modeling, 2019, 59(7), 3177-3190.

AbstractFull Text at the ACS Website — PMID: 31257873

Homology modeling of a Class A GPCR in the inactive conformation: A quantitative analysis of the correlation between model/template sequence identity and model accuracy.

Costanzi S, Skorski M, Deplano A, Habermehl B, Mendoza M, Wang K, Biederman M, Dawson J, Gao J.

Journal of Molecular Graphics and Modeling, 2016, 70, 140-152.

AbstractFull Text at the Elsevier Website — PMID: 27723562 — PMCID: PMC5138091

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.

Trivellin G. et al.

New England Journal of Medicine, 2014, 18, 371(25), 2363-74

AbstractFull Text at the NEJM Website —PMID: 25470569 — PMCID: PMC4291174